WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:
Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway       Name:Huntington's disease       ID:05016
C=183; O=82; E=4.75; R=17.25; rawP=1.18e-79; adjP=1.85e-77
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000182158 NA CREB3L2 cAMP responsive element binding protein 3-like 2 64764 ENSG00000182158
2  ENSG00000151366 NA NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 4718 ENSG00000151366
3  ENSG00000128609 NA NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa 4698 ENSG00000128609
4  ENSG00000165264 NA NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 4712 ENSG00000165264
5  ENSG00000156467 NA UQCRB ubiquinol-cytochrome c reductase binding protein 7381 ENSG00000156467
6  ENSG00000100142 NA POLR2F polymerase (RNA) II (DNA directed) polypeptide F 5435 ENSG00000100142
7  ENSG00000184076 NA UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 29796 ENSG00000184076
8  ENSG00000161281 NA COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 1346 ENSG00000161281
9  ENSG00000136521 NA NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 4711 ENSG00000136521
10  ENSG00000004779 NA NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 4706 ENSG00000004779
11  ENSG00000156885 NA COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 1339 ENSG00000156885
12  ENSG00000169375 NA SIN3A SIN3 transcription regulator homolog A (yeast) 25942 ENSG00000169375
13  ENSG00000147123 NA NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 54539 ENSG00000147123
14  ENSG00000154723 NA ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 522 ENSG00000154723
15  ENSG00000119013 NA NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 4709 ENSG00000119013
16  ENSG00000169021 NA UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 7386 ENSG00000169021
17  ENSG00000135390 NA ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 517 ENSG00000135390
18  ENSG00000166136 NA NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 4714 ENSG00000166136
19  ENSG00000078668 NA VDAC3 voltage-dependent anion channel 3 7419 ENSG00000078668
20  ENSG00000147684 NA NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 4715 ENSG00000147684
21  ENSG00000160194 NA NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa 4731 ENSG00000160194
22  ENSG00000184983 NA NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 4700 ENSG00000184983
23  ENSG00000158864 NA NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 4720 ENSG00000158864
24  ENSG00000100246 NA DNAL4 dynein, axonemal, light chain 4 10126 ENSG00000100246
25  ENSG00000139180 NA NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 4704 ENSG00000139180
26  ENSG00000142168 NA SOD1 superoxide dismutase 1, soluble 6647 ENSG00000142168
27  ENSG00000109390 NA NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 4717 ENSG00000109390
28  ENSG00000127184 NA COX7C cytochrome c oxidase subunit VIIc 1350 ENSG00000127184
29  ENSG00000177700 NA POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 5441 ENSG00000177700
30  ENSG00000164405 NA UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 27089 ENSG00000164405
31  ENSG00000165637 NA VDAC2 voltage-dependent anion channel 2 7417 ENSG00000165637
32  ENSG00000124172 NA ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 514 ENSG00000124172
33  ENSG00000213585 NA VDAC1 voltage-dependent anion channel 1 7416 ENSG00000213585
34  ENSG00000183648 NA NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 4707 ENSG00000183648
35  ENSG00000099624 NA ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 513 ENSG00000099624
36  ENSG00000116459 NA ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 515 ENSG00000116459
37  ENSG00000204370 NA SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 6392 ENSG00000204370
38  ENSG00000151729 NA SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 291 ENSG00000151729
39  ENSG00000125356 NA NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 4694 ENSG00000125356
40  ENSG00000178741 NA COX5A cytochrome c oxidase subunit Va 9377 ENSG00000178741
41  ENSG00000213619 NA NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 4722 ENSG00000213619
42  ENSG00000173660 NA UQCRH ubiquinol-cytochrome c reductase hinge protein 7388 ENSG00000173660
43  ENSG00000099795 NA NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 4713 ENSG00000099795
44  ENSG00000119421 NA NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 4702 ENSG00000119421
45  ENSG00000126267 NA COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 1340 ENSG00000126267
46  ENSG00000135940 NA COX5B cytochrome c oxidase subunit Vb 1329 ENSG00000135940
47  ENSG00000147669 NA POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa 5440 ENSG00000147669
48  ENSG00000145494 NA NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 4726 ENSG00000145494
49  ENSG00000172115 NA CYCS cytochrome c, somatic 54205 ENSG00000172115
50  ENSG00000189043 NA NDUFA4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa 4697 ENSG00000189043
51  ENSG00000131143 NA COX4I1 cytochrome c oxidase subunit IV isoform 1 1327 ENSG00000131143
52  ENSG00000164919 NA COX6C cytochrome c oxidase subunit VIc 1345 ENSG00000164919
53  ENSG00000115286 NA NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 374291 ENSG00000115286
54  ENSG00000112695 NA COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 1347 ENSG00000112695
55  ENSG00000164258 NA NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 4724 ENSG00000164258
56  ENSG00000167792 NA NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 4723 ENSG00000167792
57  ENSG00000131495 NA NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 4695 ENSG00000131495
58  ENSG00000065518 NA NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 4710 ENSG00000065518
59  ENSG00000167863 NA ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 10476 ENSG00000167863
60  ENSG00000090266 NA NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 4708 ENSG00000090266
61  ENSG00000110717 NA NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 4728 ENSG00000110717
62  ENSG00000127540 NA UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 10975 ENSG00000127540
63  ENSG00000179091 NA CYC1 cytochrome c-1 1537 ENSG00000179091
64  ENSG00000131174 NA COX7B cytochrome c oxidase subunit VIIb 1349 ENSG00000131174
65  ENSG00000184752 NA NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 55967 ENSG00000184752
66  ENSG00000170906 NA NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 4696 ENSG00000170906
67  ENSG00000185591 NA SP1 Sp1 transcription factor 6667 ENSG00000185591
68  ENSG00000159199 NA ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 516 ENSG00000159199
69  ENSG00000127946 NA HIP1 huntingtin interacting protein 1 3092 ENSG00000127946
70  ENSG00000010256 NA UQCRC1 ubiquinol-cytochrome c reductase core protein I 7384 ENSG00000010256
71  ENSG00000182621 NA PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 23236 ENSG00000182621
72  ENSG00000140990 NA NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 4716 ENSG00000140990
73  ENSG00000181222 NA POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 5430 ENSG00000181222
74  ENSG00000117118 NA SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 6390 ENSG00000117118
75  ENSG00000005075 NA POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa 5439 ENSG00000005075
76  ENSG00000154518 NA ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 518 ENSG00000154518
77  ENSG00000165629 NA ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 509 ENSG00000165629
78  ENSG00000115944 NA COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 9167 ENSG00000115944
79  ENSG00000176340 NA COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1351 ENSG00000176340
80  ENSG00000099817 NA POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 5434 ENSG00000099817
81  ENSG00000168653 NA NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 4725 ENSG00000168653
82  ENSG00000241837 NA ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 539 ENSG00000241837


Database:KEGG pathway       Name:Oxidative phosphorylation       ID:00190
C=132; O=72; E=3.43; R=21.00; rawP=3.65e-78; adjP=2.87e-76
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000151366 NA NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 4718 ENSG00000151366
2  ENSG00000128609 NA NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa 4698 ENSG00000128609
3  ENSG00000165264 NA NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 4712 ENSG00000165264
4  ENSG00000156467 NA UQCRB ubiquinol-cytochrome c reductase binding protein 7381 ENSG00000156467
5  ENSG00000184076 NA UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 29796 ENSG00000184076
6  ENSG00000161281 NA COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 1346 ENSG00000161281
7  ENSG00000136521 NA NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 4711 ENSG00000136521
8  ENSG00000004779 NA NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 4706 ENSG00000004779
9  ENSG00000156885 NA COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 1339 ENSG00000156885
10  ENSG00000147123 NA NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 54539 ENSG00000147123
11  ENSG00000154723 NA ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 522 ENSG00000154723
12  ENSG00000119013 NA NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 4709 ENSG00000119013
13  ENSG00000169021 NA UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 7386 ENSG00000169021
14  ENSG00000135390 NA ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 517 ENSG00000135390
15  ENSG00000166136 NA NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 4714 ENSG00000166136
16  ENSG00000147684 NA NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 4715 ENSG00000147684
17  ENSG00000160194 NA NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa 4731 ENSG00000160194
18  ENSG00000184983 NA NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 4700 ENSG00000184983
19  ENSG00000158864 NA NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 4720 ENSG00000158864
20  ENSG00000171130 NA ATP6V0E2 ATPase, H+ transporting V0 subunit e2 155066 ENSG00000171130
21  ENSG00000136888 NA ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 9550 ENSG00000136888
22  ENSG00000139180 NA NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 4704 ENSG00000139180
23  ENSG00000109390 NA NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 4717 ENSG00000109390
24  ENSG00000127184 NA COX7C cytochrome c oxidase subunit VIIc 1350 ENSG00000127184
25  ENSG00000164405 NA UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 27089 ENSG00000164405
26  ENSG00000124172 NA ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 514 ENSG00000124172
27  ENSG00000183648 NA NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 4707 ENSG00000183648
28  ENSG00000099624 NA ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 513 ENSG00000099624
29  ENSG00000116459 NA ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 515 ENSG00000116459
30  ENSG00000204370 NA SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 6392 ENSG00000204370
31  ENSG00000125356 NA NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 4694 ENSG00000125356
32  ENSG00000138777 NA PPA2 pyrophosphatase (inorganic) 2 27068 ENSG00000138777
33  ENSG00000178741 NA COX5A cytochrome c oxidase subunit Va 9377 ENSG00000178741
34  ENSG00000213619 NA NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 4722 ENSG00000213619
35  ENSG00000173660 NA UQCRH ubiquinol-cytochrome c reductase hinge protein 7388 ENSG00000173660
36  ENSG00000099795 NA NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 4713 ENSG00000099795
37  ENSG00000119421 NA NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 4702 ENSG00000119421
38  ENSG00000126267 NA COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 1340 ENSG00000126267
39  ENSG00000135940 NA COX5B cytochrome c oxidase subunit Vb 1329 ENSG00000135940
40  ENSG00000145494 NA NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 4726 ENSG00000145494
41  ENSG00000189043 NA NDUFA4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa 4697 ENSG00000189043
42  ENSG00000131143 NA COX4I1 cytochrome c oxidase subunit IV isoform 1 1327 ENSG00000131143
43  ENSG00000164919 NA COX6C cytochrome c oxidase subunit VIc 1345 ENSG00000164919
44  ENSG00000115286 NA NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 374291 ENSG00000115286
45  ENSG00000112695 NA COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 1347 ENSG00000112695
46  ENSG00000164258 NA NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 4724 ENSG00000164258
47  ENSG00000167792 NA NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 4723 ENSG00000167792
48  ENSG00000131495 NA NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 4695 ENSG00000131495
49  ENSG00000065518 NA NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 4710 ENSG00000065518
50  ENSG00000167863 NA ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 10476 ENSG00000167863
51  ENSG00000090266 NA NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 4708 ENSG00000090266
52  ENSG00000110717 NA NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 4728 ENSG00000110717
53  ENSG00000179091 NA CYC1 cytochrome c-1 1537 ENSG00000179091
54  ENSG00000127540 NA UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 10975 ENSG00000127540
55  ENSG00000131174 NA COX7B cytochrome c oxidase subunit VIIb 1349 ENSG00000131174
56  ENSG00000047249 NA ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 51606 ENSG00000047249
57  ENSG00000184752 NA NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 55967 ENSG00000184752
58  ENSG00000170906 NA NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 4696 ENSG00000170906
59  ENSG00000159199 NA ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 516 ENSG00000159199
60  ENSG00000167283 NA ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G 10632 ENSG00000167283
61  ENSG00000010256 NA UQCRC1 ubiquinol-cytochrome c reductase core protein I 7384 ENSG00000010256
62  ENSG00000241468 NA ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 9551 ENSG00000241468
63  ENSG00000140990 NA NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 4716 ENSG00000140990
64  ENSG00000117118 NA SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 6390 ENSG00000117118
65  ENSG00000138495 NA COX17 COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) 10063 ENSG00000138495
66  ENSG00000100554 NA ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 51382 ENSG00000100554
67  ENSG00000154518 NA ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 518 ENSG00000154518
68  ENSG00000165629 NA ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 509 ENSG00000165629
69  ENSG00000115944 NA COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 9167 ENSG00000115944
70  ENSG00000176340 NA COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1351 ENSG00000176340
71  ENSG00000168653 NA NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 4725 ENSG00000168653
72  ENSG00000241837 NA ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 539 ENSG00000241837


Database:KEGG pathway       Name:Parkinson's disease       ID:05012
C=130; O=71; E=3.38; R=21.03; rawP=3.83e-77; adjP=2.00e-75
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000151366 NA NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 4718 ENSG00000151366
2  ENSG00000128609 NA NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa 4698 ENSG00000128609
3  ENSG00000165264 NA NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 4712 ENSG00000165264
4  ENSG00000156467 NA UQCRB ubiquinol-cytochrome c reductase binding protein 7381 ENSG00000156467
5  ENSG00000184076 NA UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 29796 ENSG00000184076
6  ENSG00000161281 NA COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 1346 ENSG00000161281
7  ENSG00000136521 NA NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 4711 ENSG00000136521
8  ENSG00000004779 NA NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 4706 ENSG00000004779
9  ENSG00000156885 NA COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 1339 ENSG00000156885
10  ENSG00000147123 NA NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 54539 ENSG00000147123
11  ENSG00000154723 NA ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 522 ENSG00000154723
12  ENSG00000116288 NA PARK7 parkinson protein 7 11315 ENSG00000116288
13  ENSG00000119013 NA NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 4709 ENSG00000119013
14  ENSG00000169021 NA UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 7386 ENSG00000169021
15  ENSG00000135390 NA ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 517 ENSG00000135390
16  ENSG00000166136 NA NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 4714 ENSG00000166136
17  ENSG00000078668 NA VDAC3 voltage-dependent anion channel 3 7419 ENSG00000078668
18  ENSG00000147684 NA NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 4715 ENSG00000147684
19  ENSG00000160194 NA NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa 4731 ENSG00000160194
20  ENSG00000184983 NA NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 4700 ENSG00000184983
21  ENSG00000158864 NA NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 4720 ENSG00000158864
22  ENSG00000139180 NA NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 4704 ENSG00000139180
23  ENSG00000109390 NA NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 4717 ENSG00000109390
24  ENSG00000127184 NA COX7C cytochrome c oxidase subunit VIIc 1350 ENSG00000127184
25  ENSG00000164405 NA UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 27089 ENSG00000164405
26  ENSG00000165637 NA VDAC2 voltage-dependent anion channel 2 7417 ENSG00000165637
27  ENSG00000124172 NA ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 514 ENSG00000124172
28  ENSG00000213585 NA VDAC1 voltage-dependent anion channel 1 7416 ENSG00000213585
29  ENSG00000183648 NA NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 4707 ENSG00000183648
30  ENSG00000099624 NA ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 513 ENSG00000099624
31  ENSG00000116459 NA ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 515 ENSG00000116459
32  ENSG00000204370 NA SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 6392 ENSG00000204370
33  ENSG00000151729 NA SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 291 ENSG00000151729
34  ENSG00000125356 NA NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 4694 ENSG00000125356
35  ENSG00000178741 NA COX5A cytochrome c oxidase subunit Va 9377 ENSG00000178741
36  ENSG00000213619 NA NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 4722 ENSG00000213619
37  ENSG00000173660 NA UQCRH ubiquinol-cytochrome c reductase hinge protein 7388 ENSG00000173660
38  ENSG00000099795 NA NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 4713 ENSG00000099795
39  ENSG00000119421 NA NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 4702 ENSG00000119421
40  ENSG00000126267 NA COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 1340 ENSG00000126267
41  ENSG00000135940 NA COX5B cytochrome c oxidase subunit Vb 1329 ENSG00000135940
42  ENSG00000145494 NA NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 4726 ENSG00000145494
43  ENSG00000172115 NA CYCS cytochrome c, somatic 54205 ENSG00000172115
44  ENSG00000189043 NA NDUFA4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa 4697 ENSG00000189043
45  ENSG00000131143 NA COX4I1 cytochrome c oxidase subunit IV isoform 1 1327 ENSG00000131143
46  ENSG00000164919 NA COX6C cytochrome c oxidase subunit VIc 1345 ENSG00000164919
47  ENSG00000115286 NA NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 374291 ENSG00000115286
48  ENSG00000112695 NA COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 1347 ENSG00000112695
49  ENSG00000164258 NA NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 4724 ENSG00000164258
50  ENSG00000167792 NA NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 4723 ENSG00000167792
51  ENSG00000131495 NA NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 4695 ENSG00000131495
52  ENSG00000065518 NA NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 4710 ENSG00000065518
53  ENSG00000167863 NA ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 10476 ENSG00000167863
54  ENSG00000090266 NA NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 4708 ENSG00000090266
55  ENSG00000110717 NA NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 4728 ENSG00000110717
56  ENSG00000127540 NA UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 10975 ENSG00000127540
57  ENSG00000179091 NA CYC1 cytochrome c-1 1537 ENSG00000179091
58  ENSG00000131174 NA COX7B cytochrome c oxidase subunit VIIb 1349 ENSG00000131174
59  ENSG00000170315 NA UBB ubiquitin B 7314 ENSG00000170315
60  ENSG00000184752 NA NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 55967 ENSG00000184752
61  ENSG00000170906 NA NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 4696 ENSG00000170906
62  ENSG00000159199 NA ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 516 ENSG00000159199
63  ENSG00000010256 NA UQCRC1 ubiquinol-cytochrome c reductase core protein I 7384 ENSG00000010256
64  ENSG00000140990 NA NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 4716 ENSG00000140990
65  ENSG00000117118 NA SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 6390 ENSG00000117118
66  ENSG00000154518 NA ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 518 ENSG00000154518
67  ENSG00000165629 NA ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 509 ENSG00000165629
68  ENSG00000115944 NA COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 9167 ENSG00000115944
69  ENSG00000176340 NA COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1351 ENSG00000176340
70  ENSG00000168653 NA NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 4725 ENSG00000168653
71  ENSG00000241837 NA ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 539 ENSG00000241837


Database:KEGG pathway       Name:Alzheimer's disease       ID:05010
C=167; O=72; E=4.34; R=16.60; rawP=1.69e-68; adjP=6.63e-67
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000151366 NA NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 4718 ENSG00000151366
2  ENSG00000128609 NA NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa 4698 ENSG00000128609
3  ENSG00000165264 NA NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 4712 ENSG00000165264
4  ENSG00000156467 NA UQCRB ubiquinol-cytochrome c reductase binding protein 7381 ENSG00000156467
5  ENSG00000184076 NA UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 29796 ENSG00000184076
6  ENSG00000161281 NA COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 1346 ENSG00000161281
7  ENSG00000136521 NA NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 4711 ENSG00000136521
8  ENSG00000004779 NA NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 4706 ENSG00000004779
9  ENSG00000156885 NA COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 1339 ENSG00000156885
10  ENSG00000147123 NA NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 54539 ENSG00000147123
11  ENSG00000154723 NA ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 522 ENSG00000154723
12  ENSG00000119013 NA NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 4709 ENSG00000119013
13  ENSG00000169021 NA UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 7386 ENSG00000169021
14  ENSG00000143933 NA CALM2 calmodulin 2 (phosphorylase kinase, delta) 805 ENSG00000143933
15  ENSG00000135390 NA ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 517 ENSG00000135390
16  ENSG00000166136 NA NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 4714 ENSG00000166136
17  ENSG00000147684 NA NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 4715 ENSG00000147684
18  ENSG00000160194 NA NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa 4731 ENSG00000160194
19  ENSG00000184983 NA NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 4700 ENSG00000184983
20  ENSG00000158864 NA NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 4720 ENSG00000158864
21  ENSG00000159593 NA NAE1 NEDD8 activating enzyme E1 subunit 1 8883 ENSG00000159593
22  ENSG00000139180 NA NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 4704 ENSG00000139180
23  ENSG00000109390 NA NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 4717 ENSG00000109390
24  ENSG00000111640 NA GAPDH glyceraldehyde-3-phosphate dehydrogenase 2597 ENSG00000111640
25  ENSG00000127184 NA COX7C cytochrome c oxidase subunit VIIc 1350 ENSG00000127184
26  ENSG00000164405 NA UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 27089 ENSG00000164405
27  ENSG00000124172 NA ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 514 ENSG00000124172
28  ENSG00000183648 NA NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 4707 ENSG00000183648
29  ENSG00000099624 NA ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 513 ENSG00000099624
30  ENSG00000116459 NA ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 515 ENSG00000116459
31  ENSG00000204370 NA SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 6392 ENSG00000204370
32  ENSG00000125356 NA NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 4694 ENSG00000125356
33  ENSG00000178741 NA COX5A cytochrome c oxidase subunit Va 9377 ENSG00000178741
34  ENSG00000213619 NA NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 4722 ENSG00000213619
35  ENSG00000173660 NA UQCRH ubiquinol-cytochrome c reductase hinge protein 7388 ENSG00000173660
36  ENSG00000099795 NA NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 4713 ENSG00000099795
37  ENSG00000119421 NA NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 4702 ENSG00000119421
38  ENSG00000126267 NA COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 1340 ENSG00000126267
39  ENSG00000135940 NA COX5B cytochrome c oxidase subunit Vb 1329 ENSG00000135940
40  ENSG00000186318 NA BACE1 beta-site APP-cleaving enzyme 1 23621 ENSG00000265969 ENSG00000186318
41  ENSG00000145494 NA NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 4726 ENSG00000145494
42  ENSG00000072506 NA HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 3028 ENSG00000072506
43  ENSG00000172115 NA CYCS cytochrome c, somatic 54205 ENSG00000172115
44  ENSG00000189043 NA NDUFA4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa 4697 ENSG00000189043
45  ENSG00000131143 NA COX4I1 cytochrome c oxidase subunit IV isoform 1 1327 ENSG00000131143
46  ENSG00000164919 NA COX6C cytochrome c oxidase subunit VIc 1345 ENSG00000164919
47  ENSG00000115286 NA NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 374291 ENSG00000115286
48  ENSG00000112695 NA COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 1347 ENSG00000112695
49  ENSG00000164258 NA NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 4724 ENSG00000164258
50  ENSG00000167792 NA NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 4723 ENSG00000167792
51  ENSG00000131495 NA NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 4695 ENSG00000131495
52  ENSG00000065518 NA NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 4710 ENSG00000065518
53  ENSG00000167863 NA ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 10476 ENSG00000167863
54  ENSG00000090266 NA NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 4708 ENSG00000090266
55  ENSG00000110717 NA NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 4728 ENSG00000110717
56  ENSG00000127540 NA UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 10975 ENSG00000127540
57  ENSG00000179091 NA CYC1 cytochrome c-1 1537 ENSG00000179091
58  ENSG00000131174 NA COX7B cytochrome c oxidase subunit VIIb 1349 ENSG00000131174
59  ENSG00000184752 NA NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 55967 ENSG00000184752
60  ENSG00000170906 NA NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 4696 ENSG00000170906
61  ENSG00000159199 NA ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 516 ENSG00000159199
62  ENSG00000198668 NA CALM1 calmodulin 1 (phosphorylase kinase, delta) 801 ENSG00000198668
63  ENSG00000010256 NA UQCRC1 ubiquinol-cytochrome c reductase core protein I 7384 ENSG00000010256
64  ENSG00000182621 NA PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 23236 ENSG00000182621
65  ENSG00000140990 NA NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 4716 ENSG00000140990
66  ENSG00000117118 NA SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 6390 ENSG00000117118
67  ENSG00000154518 NA ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 518 ENSG00000154518
68  ENSG00000165629 NA ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 509 ENSG00000165629
69  ENSG00000115944 NA COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 9167 ENSG00000115944
70  ENSG00000176340 NA COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1351 ENSG00000176340
71  ENSG00000168653 NA NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 4725 ENSG00000168653
72  ENSG00000241837 NA ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 539 ENSG00000241837


Database:KEGG pathway       Name:Metabolic pathways       ID:01100
C=1130; O=153; E=29.35; R=5.21; rawP=1.73e-64; adjP=5.43e-63
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000127125 NA PPCS phosphopantothenoylcysteine synthetase 79717 ENSG00000127125
2  ENSG00000187630 NA DHRS4L2 dehydrogenase/reductase (SDR family) member 4 like 2 317749 ENSG00000187630
3  ENSG00000165264 NA NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 4712 ENSG00000165264
4  ENSG00000156467 NA UQCRB ubiquinol-cytochrome c reductase binding protein 7381 ENSG00000156467
5  ENSG00000100142 NA POLR2F polymerase (RNA) II (DNA directed) polypeptide F 5435 ENSG00000100142
6  ENSG00000184076 NA UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 29796 ENSG00000184076
7  ENSG00000148672 NA GLUD1 glutamate dehydrogenase 1 2746 ENSG00000148672
8  ENSG00000156885 NA COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 1339 ENSG00000156885
9  ENSG00000105607 NA GCDH glutaryl-CoA dehydrogenase 2639 ENSG00000105607
10  ENSG00000122643 NA NT5C3 5'-nucleotidase, cytosolic III 51251 ENSG00000122643
11  ENSG00000154723 NA ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 522 ENSG00000154723
12  ENSG00000105552 NA BCAT2 branched chain amino-acid transaminase 2, mitochondrial 587 ENSG00000105552
13  ENSG00000160282 NA FTCD formiminotransferase cyclodeaminase 10841 ENSG00000160282
14  ENSG00000131069 NA ACSS2 acyl-CoA synthetase short-chain family member 2 55902 ENSG00000131069
15  ENSG00000135390 NA ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 517 ENSG00000135390
16  ENSG00000166136 NA NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 4714 ENSG00000166136
17  ENSG00000116353 NA MECR mitochondrial trans-2-enoyl-CoA reductase 51102 ENSG00000116353
18  ENSG00000085662 NA AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 231 ENSG00000085662
19  ENSG00000172340 NA SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 8801 ENSG00000172340
20  ENSG00000147684 NA NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 4715 ENSG00000147684
21  ENSG00000160194 NA NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa 4731 ENSG00000160194
22  ENSG00000151093 NA OXSM 3-oxoacyl-ACP synthase, mitochondrial 54995 ENSG00000151093
23  ENSG00000184983 NA NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 4700 ENSG00000184983
24  ENSG00000158864 NA NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 4720 ENSG00000158864
25  ENSG00000169826 NA CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 55454 ENSG00000169826
26  ENSG00000131828 NA PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 5160 ENSG00000131828
27  ENSG00000122971 NA ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 35 ENSG00000122971
28  ENSG00000109390 NA NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 4717 ENSG00000109390
29  ENSG00000091483 NA FH fumarate hydratase 2271 ENSG00000091483
30  ENSG00000109586 NA GALNT7 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7) 51809 ENSG00000109586
31  ENSG00000168291 NA PDHB pyruvate dehydrogenase (lipoamide) beta 5162 ENSG00000168291
32  ENSG00000148334 NA PTGES2 prostaglandin E synthase 2 80142 ENSG00000148334
33  ENSG00000116459 NA ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 515 ENSG00000116459
34  ENSG00000128311 NA TST thiosulfate sulfurtransferase (rhodanese) 7263 ENSG00000128311
35  ENSG00000119537 NA KDSR 3-ketodihydrosphingosine reductase 2531 ENSG00000119537
36  ENSG00000149925 NA ALDOA aldolase A, fructose-bisphosphate 226 ENSG00000149925
37  ENSG00000178741 NA COX5A cytochrome c oxidase subunit Va 9377 ENSG00000178741
38  ENSG00000213619 NA NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 4722 ENSG00000213619
39  ENSG00000173660 NA UQCRH ubiquinol-cytochrome c reductase hinge protein 7388 ENSG00000173660
40  ENSG00000164574 NA GALNT10 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10) 55568 ENSG00000164574
41  ENSG00000119421 NA NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 4702 ENSG00000119421
42  ENSG00000126267 NA COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 1340 ENSG00000126267
43  ENSG00000104879 NA CKM creatine kinase, muscle 1158 ENSG00000104879
44  ENSG00000093217 NA XYLB xylulokinase homolog (H. influenzae) 9942 ENSG00000093217
45  ENSG00000125779 NA PANK2 pantothenate kinase 2 80025 ENSG00000125779
46  ENSG00000135940 NA COX5B cytochrome c oxidase subunit Vb 1329 ENSG00000135940
47  ENSG00000147669 NA POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa 5440 ENSG00000147669
48  ENSG00000145494 NA NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 4726 ENSG00000145494
49  ENSG00000072506 NA HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 3028 ENSG00000072506
50  ENSG00000131143 NA COX4I1 cytochrome c oxidase subunit IV isoform 1 1327 ENSG00000131143
51  ENSG00000189043 NA NDUFA4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa 4697 ENSG00000189043
52  ENSG00000179085 NA DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 54344 ENSG00000179085
53  ENSG00000164919 NA COX6C cytochrome c oxidase subunit VIc 1345 ENSG00000164919
54  ENSG00000185100 NA ADSSL1 adenylosuccinate synthase like 1 122622 ENSG00000185100
55  ENSG00000115286 NA NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 374291 ENSG00000115286
56  ENSG00000164258 NA NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 4724 ENSG00000164258
57  ENSG00000167863 NA ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 10476 ENSG00000167863
58  ENSG00000090266 NA NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 4708 ENSG00000090266
59  ENSG00000108515 NA ENO3 enolase 3 (beta, muscle) 2027 ENSG00000108515
60  ENSG00000127540 NA UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 10975 ENSG00000127540
61  ENSG00000166165 NA CKB creatine kinase, brain 1152 ENSG00000166165
62  ENSG00000179091 NA CYC1 cytochrome c-1 1537 ENSG00000179091
63  ENSG00000047249 NA ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 51606 ENSG00000047249
64  ENSG00000132423 NA COQ3 coenzyme Q3 homolog, methyltransferase (S. cerevisiae) 51805 ENSG00000132423
65  ENSG00000033011 NA ALG1 asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae) 56052 ENSG00000033011
66  ENSG00000198108 NA CHSY3 chondroitin sulfate synthase 3 337876 ENSG00000198108
67  ENSG00000159199 NA ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 516 ENSG00000159199
68  ENSG00000087157 NA PGS1 phosphatidylglycerophosphate synthase 1 9489 ENSG00000087157
69  ENSG00000175198 NA PCCA propionyl CoA carboxylase, alpha polypeptide 5095 ENSG00000175198
70  ENSG00000067829 NA IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 3421 ENSG00000067829
71  ENSG00000177628 NA GBA glucosidase, beta, acid 2629 ENSG00000177628
72  ENSG00000129187 NA DCTD dCMP deaminase 1635 ENSG00000129187
73  ENSG00000182621 NA PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 23236 ENSG00000182621
74  ENSG00000152556 NA PFKM phosphofructokinase, muscle 5213 ENSG00000152556
75  ENSG00000140990 NA NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 4716 ENSG00000140990
76  ENSG00000157326 NA DHRS4 dehydrogenase/reductase (SDR family) member 4 10901 ENSG00000157326
77  ENSG00000138495 NA COX17 COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) 10063 ENSG00000138495
78  ENSG00000117118 NA SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 6390 ENSG00000117118
79  ENSG00000035687 NA ADSS adenylosuccinate synthase 159 ENSG00000035687
80  ENSG00000167701 NA GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2875 ENSG00000167701
81  ENSG00000184207 NA PGP phosphoglycolate phosphatase 283871 ENSG00000184207
82  ENSG00000005075 NA POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa 5439 ENSG00000005075
83  ENSG00000165629 NA ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 509 ENSG00000165629
84  ENSG00000130035 NA GALNT8 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8) 26290 ENSG00000130035
85  ENSG00000099817 NA POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 5434 ENSG00000099817
86  ENSG00000100294 NA MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 27349 ENSG00000100294
87  ENSG00000014641 NA MDH1 malate dehydrogenase 1, NAD (soluble) 4190 ENSG00000014641
88  ENSG00000105220 NA GPI glucose-6-phosphate isomerase 2821 ENSG00000105220
89  ENSG00000154930 NA ACSS1 acyl-CoA synthetase short-chain family member 1 84532 ENSG00000154930
90  ENSG00000128609 NA NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa 4698 ENSG00000128609
91  ENSG00000151366 NA NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 4718 ENSG00000151366
92  ENSG00000163541 NA SUCLG1 succinate-CoA ligase, alpha subunit 8802 ENSG00000163541
93  ENSG00000112981 NA NME5 NME/NM23 family member 5 8382 ENSG00000112981
94  ENSG00000146701 NA MDH2 malate dehydrogenase 2, NAD (mitochondrial) 4191 ENSG00000146701
95  ENSG00000103489 NA XYLT1 xylosyltransferase I 64131 ENSG00000103489
96  ENSG00000136521 NA NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 4711 ENSG00000136521
97  ENSG00000004779 NA NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 4706 ENSG00000004779
98  ENSG00000182054 NA IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 3418 ENSG00000182054
99  ENSG00000131730 NA CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1160 ENSG00000131730
100  ENSG00000151348 NA EXT2 exostosin 2 2132 ENSG00000151348
101  ENSG00000119013 NA NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 4709 ENSG00000119013
102  ENSG00000115652 NA UXS1 UDP-glucuronate decarboxylase 1 80146 ENSG00000115652
103  ENSG00000169021 NA UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 7386 ENSG00000169021
104  ENSG00000128951 NA DUT deoxyuridine triphosphatase 1854 ENSG00000128951
105  ENSG00000177156 NA TALDO1 transaldolase 1 6888 ENSG00000177156
106  ENSG00000139428 NA MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 326625 ENSG00000139428
107  ENSG00000171130 NA ATP6V0E2 ATPase, H+ transporting V0 subunit e2 155066 ENSG00000171130
108  ENSG00000136888 NA ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 9550 ENSG00000136888
109  ENSG00000124370 NA MCEE methylmalonyl CoA epimerase 84693 ENSG00000124370
110  ENSG00000139180 NA NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 4704 ENSG00000139180
111  ENSG00000111640 NA GAPDH glyceraldehyde-3-phosphate dehydrogenase 2597 ENSG00000111640
112  ENSG00000127184 NA COX7C cytochrome c oxidase subunit VIIc 1350 ENSG00000127184
113  ENSG00000188690 NA UROS uroporphyrinogen III synthase 7390 ENSG00000188690
114  ENSG00000177700 NA POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 5441 ENSG00000177700
115  ENSG00000164405 NA UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 27089 ENSG00000164405
116  ENSG00000124172 NA ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 514 ENSG00000124172
117  ENSG00000183648 NA NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 4707 ENSG00000183648
118  ENSG00000099624 NA ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 513 ENSG00000099624
119  ENSG00000204370 NA SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 6392 ENSG00000204370
120  ENSG00000137106 NA GRHPR glyoxylate reductase/hydroxypyruvate reductase 9380 ENSG00000137106
121  ENSG00000169738 NA DCXR dicarbonyl/L-xylulose reductase 51181 ENSG00000169738
122  ENSG00000125356 NA NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 4694 ENSG00000125356
123  ENSG00000099795 NA NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 4713 ENSG00000099795
124  ENSG00000153574 NA RPIA ribose 5-phosphate isomerase A 22934 ENSG00000153574
125  ENSG00000198814 NA GK glycerol kinase 2710 ENSG00000198814
126  ENSG00000121897 NA LIAS lipoic acid synthetase 11019 ENSG00000121897
127  ENSG00000060971 NA ACAA1 acetyl-CoA acyltransferase 1 30 ENSG00000060971
128  ENSG00000147155 NA EBP emopamil binding protein (sterol isomerase) 10682 ENSG00000147155
129  ENSG00000167792 NA NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 4723 ENSG00000167792
130  ENSG00000171097 NA CCBL1 cysteine conjugate-beta lyase, cytoplasmic 883 ENSG00000171097
131  ENSG00000131495 NA NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 4695 ENSG00000131495
132  ENSG00000065518 NA NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 4710 ENSG00000065518
133  ENSG00000151552 NA QDPR quinoid dihydropteridine reductase 5860 ENSG00000151552
134  ENSG00000185808 NA PIGP phosphatidylinositol glycan anchor biosynthesis, class P 51227 ENSG00000185808
135  ENSG00000110717 NA NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 4728 ENSG00000110717
136  ENSG00000131174 NA COX7B cytochrome c oxidase subunit VIIb 1349 ENSG00000131174
137  ENSG00000170906 NA NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 4696 ENSG00000170906
138  ENSG00000205309 NA NT5M 5',3'-nucleotidase, mitochondrial 56953 ENSG00000205309
139  ENSG00000111716 NA LDHB lactate dehydrogenase B 3945 ENSG00000111716
140  ENSG00000167283 NA ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G 10632 ENSG00000167283
141  ENSG00000127884 NA ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 1892 ENSG00000127884
142  ENSG00000010256 NA UQCRC1 ubiquinol-cytochrome c reductase core protein I 7384 ENSG00000010256
143  ENSG00000241468 NA ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 9551 ENSG00000241468
144  ENSG00000181222 NA POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 5430 ENSG00000181222
145  ENSG00000100554 NA ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 51382 ENSG00000100554
146  ENSG00000138796 NA HADH hydroxyacyl-CoA dehydrogenase 3033 ENSG00000138796
147  ENSG00000154518 NA ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 518 ENSG00000154518
148  ENSG00000107317 NA PTGDS prostaglandin D2 synthase 21kDa (brain) 5730 ENSG00000107317
149  ENSG00000176340 NA COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1351 ENSG00000176340
150  ENSG00000168653 NA NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 4725 ENSG00000168653
151  ENSG00000101365 NA IDH3B isocitrate dehydrogenase 3 (NAD+) beta 3420 ENSG00000101365
152  ENSG00000141504 NA SAT2 spermidine/spermine N1-acetyltransferase family member 2 112483 ENSG00000141504
153  ENSG00000241837 NA ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 539 ENSG00000241837


Database:KEGG pathway       Name:Cardiac muscle contraction       ID:04260
C=77; O=25; E=2.00; R=12.50; rawP=5.67e-21; adjP=1.48e-19
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135940 NA COX5B cytochrome c oxidase subunit Vb 1329 ENSG00000135940
2  ENSG00000127184 NA COX7C cytochrome c oxidase subunit VIIc 1350 ENSG00000127184
3  ENSG00000129991 NA TNNI3 troponin I type 3 (cardiac) 7137 ENSG00000129991
4  ENSG00000143549 NA TPM3 tropomyosin 3 7170 ENSG00000143549
5  ENSG00000156467 NA UQCRB ubiquinol-cytochrome c reductase binding protein 7381 ENSG00000156467
6  ENSG00000164405 NA UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 27089 ENSG00000164405
7  ENSG00000184076 NA UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 29796 ENSG00000184076
8  ENSG00000161281 NA COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 1346 ENSG00000161281
9  ENSG00000131143 NA COX4I1 cytochrome c oxidase subunit IV isoform 1 1327 ENSG00000131143
10  ENSG00000010256 NA UQCRC1 ubiquinol-cytochrome c reductase core protein I 7384 ENSG00000010256
11  ENSG00000156885 NA COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 1339 ENSG00000156885
12  ENSG00000164919 NA COX6C cytochrome c oxidase subunit VIc 1345 ENSG00000164919
13  ENSG00000157445 NA CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 55799 ENSG00000157445
14  ENSG00000112695 NA COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 1347 ENSG00000112695
15  ENSG00000169021 NA UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 7386 ENSG00000169021
16  ENSG00000165995 NA CACNB2 calcium channel, voltage-dependent, beta 2 subunit 783 ENSG00000165995
17  ENSG00000115944 NA COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 9167 ENSG00000115944
18  ENSG00000176340 NA COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1351 ENSG00000176340
19  ENSG00000178741 NA COX5A cytochrome c oxidase subunit Va 9377 ENSG00000178741
20  ENSG00000173660 NA UQCRH ubiquinol-cytochrome c reductase hinge protein 7388 ENSG00000173660
21  ENSG00000127540 NA UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 10975 ENSG00000127540
22  ENSG00000179091 NA CYC1 cytochrome c-1 1537 ENSG00000179091
23  ENSG00000131174 NA COX7B cytochrome c oxidase subunit VIIb 1349 ENSG00000131174
24  ENSG00000126267 NA COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 1340 ENSG00000126267
25  ENSG00000160808 NA MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow 4634 ENSG00000160808


Database:KEGG pathway       Name:Proteasome       ID:03050
C=44; O=17; E=1.14; R=14.88; rawP=3.50e-16; adjP=7.85e-15
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000008018 NA PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 5689 ENSG00000008018
2  ENSG00000100804 NA PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 5693 ENSG00000100804
3  ENSG00000100567 NA PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 5684 ENSG00000100567
4  ENSG00000159377 NA PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 5692 ENSG00000159377
5  ENSG00000165916 NA PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 5702 ENSG00000165916
6  ENSG00000136930 NA PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 5695 ENSG00000136930
7  ENSG00000129084 NA PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 5682 ENSG00000256206 ENSG00000129084
8  ENSG00000041357 NA PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 5685 ENSG00000041357
9  ENSG00000013275 NA PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 5704 ENSG00000013275
10  ENSG00000185627 NA PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 5719 ENSG00000185627
11  ENSG00000100519 NA PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 5706 ENSG00000100519
12  ENSG00000127922 NA SHFM1 split hand/foot malformation (ectrodactyly) type 1 7979 ENSG00000127922
13  ENSG00000161057 NA PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 5701 ENSG00000161057
14  ENSG00000087191 NA PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 5705 ENSG00000087191
15  ENSG00000163636 NA PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 9861 ENSG00000163636
16  ENSG00000100764 NA PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 5700 ENSG00000100764
17  ENSG00000142507 NA PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 5694 ENSG00000142507


Database:KEGG pathway       Name:Citrate cycle (TCA cycle)       ID:00020
C=30; O=12; E=0.78; R=15.40; rawP=4.99e-12; adjP=9.79e-11
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000117118 NA SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 6390 ENSG00000117118
2  ENSG00000131828 NA PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 5160 ENSG00000131828
3  ENSG00000163541 NA SUCLG1 succinate-CoA ligase, alpha subunit 8802 ENSG00000163541
4  ENSG00000146701 NA MDH2 malate dehydrogenase 2, NAD (mitochondrial) 4191 ENSG00000146701
5  ENSG00000067829 NA IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 3421 ENSG00000067829
6  ENSG00000091483 NA FH fumarate hydratase 2271 ENSG00000091483
7  ENSG00000172340 NA SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 8801 ENSG00000172340
8  ENSG00000014641 NA MDH1 malate dehydrogenase 1, NAD (soluble) 4190 ENSG00000014641
9  ENSG00000182054 NA IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 3418 ENSG00000182054
10  ENSG00000101365 NA IDH3B isocitrate dehydrogenase 3 (NAD+) beta 3420 ENSG00000101365
11  ENSG00000168291 NA PDHB pyruvate dehydrogenase (lipoamide) beta 5162 ENSG00000168291
12  ENSG00000204370 NA SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 6392 ENSG00000204370


Database:KEGG pathway       Name:Ubiquitin mediated proteolysis       ID:04120
C=135; O=18; E=3.51; R=5.13; rawP=1.53e-08; adjP=2.67e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000103363 NA TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) 6923 ENSG00000103363
2  ENSG00000100387 NA RBX1 ring-box 1, E3 ubiquitin protein ligase 9978 ENSG00000100387
3  ENSG00000134086 NA VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 7428 ENSG00000134086
4  ENSG00000144744 NA UBA3 ubiquitin-like modifier activating enzyme 3 9039 ENSG00000144744
5  ENSG00000158290 NA CUL4B cullin 4B 8450 ENSG00000158290
6  ENSG00000077721 NA UBE2A ubiquitin-conjugating enzyme E2A 7319 ENSG00000077721
7  ENSG00000094880 NA CDC23 cell division cycle 23 homolog (S. cerevisiae) 8697 ENSG00000094880
8  ENSG00000198373 NA WWP2 WW domain containing E3 ubiquitin protein ligase 2 11060 ENSG00000198373
9  ENSG00000135679 NA MDM2 Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse) 4193 ENSG00000135679
10  ENSG00000099804 NA CDC34 cell division cycle 34 homolog (S. cerevisiae) 997 ENSG00000099804
11  ENSG00000141552 NA ANAPC11 anaphase promoting complex subunit 11 51529 ENSG00000141552
12  ENSG00000164162 NA ANAPC10 anaphase promoting complex subunit 10 10393 ENSG00000164162
13  ENSG00000078967 NA UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) 51619 ENSG00000078967
14  ENSG00000113558 NA SKP1 S-phase kinase-associated protein 1 6500 ENSG00000113558
15  ENSG00000119048 NA UBE2B ubiquitin-conjugating enzyme E2B 7320 ENSG00000119048
16  ENSG00000072401 NA UBE2D1 ubiquitin-conjugating enzyme E2D 1 7321 ENSG00000072401
17  ENSG00000130725 NA UBE2M ubiquitin-conjugating enzyme E2M 9040 ENSG00000130725
18  ENSG00000101871 NA MID1 midline 1 (Opitz/BBB syndrome) 4281 ENSG00000101871


Database:KEGG pathway       Name:Pyruvate metabolism       ID:00620
C=40; O=10; E=1.04; R=9.63; rawP=5.60e-08; adjP=8.79e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000131828 NA PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 5160 ENSG00000131828
2  ENSG00000137106 NA GRHPR glyoxylate reductase/hydroxypyruvate reductase 9380 ENSG00000137106
3  ENSG00000131069 NA ACSS2 acyl-CoA synthetase short-chain family member 2 55902 ENSG00000131069
4  ENSG00000146701 NA MDH2 malate dehydrogenase 2, NAD (mitochondrial) 4191 ENSG00000146701
5  ENSG00000085662 NA AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 231 ENSG00000085662
6  ENSG00000124767 NA GLO1 glyoxalase I 2739 ENSG00000124767
7  ENSG00000014641 NA MDH1 malate dehydrogenase 1, NAD (soluble) 4190 ENSG00000014641
8  ENSG00000154930 NA ACSS1 acyl-CoA synthetase short-chain family member 1 84532 ENSG00000154930
9  ENSG00000168291 NA PDHB pyruvate dehydrogenase (lipoamide) beta 5162 ENSG00000168291
10  ENSG00000111716 NA LDHB lactate dehydrogenase B 3945 ENSG00000111716




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).